June 4, 2025: UAlbany receives an NSF Future manufacturing research grant on Manufacturing Multi-dimensional Culture Systems with Integrated Measurement and Manipulation Technologies led by Professor Sharfstein

Partners: Neural Stem Cell Institute, Binghamton University, Hudson Valley Community College, Bronx Community College, SUNY Polytechnic Institute. 

https://www.nsf.gov/awardsearch/showAward?AWD_ID=2428289&HistoricalAwards=false 

Visit Our Newest Grant Website here

August 23, 2025: Today Headline profiles our review article on Salivary Gland Bioengineering. Congratulations to former Ph.D. Stephen (Chris) Rose, Melinda Larsen and Yubing Xie.  

October, 2025 Professor Sharfstein named a pathbreaking  researcher by University at Albany. Read more here https://www.albany.edu/news-center/news/2025-four-faculty-members-tapped-pathbreaking-research-talks  

November, 2025 Congratulations to Dr. Fernando Pesantez Torres on defending his dissertation! Way to go Fernando!!

Recent publications

Journal Articles

  1. + Ramesh, J. Castracane , M. Larsen, D.A. Nelson 2,3, S.T. Sharfstein, and Y. Xie, Cryoelectrospun elastin-alginate scaffolds support in vitro 3D epithelial-stromal cocultures for salivary tissue engineering, Gels, Gels, 11(12), 998 (2025). https://doi.org/10.3390/gels11120998.
  2. *R Pranomphon, S. Gialamoidou, M. Yamabhai, I. Jiménez del Val, and S.T. Sharfstein, Modulation of Antibody Glycosylation in Chinese Hamster Ovary Cells: An Experimental and Computational Study, Biotechnology Journal, 20:e70143 (2025). https://onlinelibrary.wiley.com/share/author/RWM2KWUSZPBVWGTV3UIZ?target=10.1002/biot.70143 
  3. *F. Pesantez Torres, *E.C. Feret, Y. Xie, and S.T. Sharfstein, Real-Time Monitoring of the Cytotoxic Effect of Oxygen-Sensitive Fluorescent Poly (Styrene-Maleic Anhydride) Nanoparticles Using Electrical-Substrate Impedance Sensing, ACS Applied Bio Materials 8 (10): 9322-9331 (2025). https://doi.org/10.1021/acsabm.5c01443
  4. *F. Pesantez Torres, # Manning, M. Paredes-Espinosa, N. Tokranova, T. Bertucci, T.R. Kiehl, J. Paluh, N. Cady, Y. Xie, and S.T. Sharfstein, 3D Flexible Self-folding Microelectrode Array for Organoid Electrophysiology Analysis, Cell Biomaterials, 100179 (2025). https://doi.org/10.1016/j.celbio.2025.100179 
  5. P. Ramesh, Pena, J.M. Morrissey, N. Moskwa, K. Tubbesing, X. Zhang, D.A. Nelson, J. Castracane, A. Khmaladze, S.T. Sharfstein, M. Larsen, Y. Xie, Cryoelectrospun elastin-alginate scaffolds as potential stromal cell delivery vehicles for remediation of fibrosis, Scientific Reports, 15: 19847 (2025). https://doi.org/10.1038/s41598-025-03822-x
  6. J. Allisha, J. Das, T. Dunnigan, S.T. Sharfstein, P. Datta, Stipulations of Cell and Gene Therapy and the ties to Biomanufacturing, Biotechnology Progress,  41(3): e3521 (2025). https://doi.org/10.1002/btpr.3521
  7. Sujith Chander Reddy Kollampally, Xulang Zhang, Nicholas Moskwa, Deirdre A. Nelson, Susan T. Sharfstein, Melinda Larsen, and Yubing Xie, Evaluation of Alginate Hydrogel Microstrands for Stromal Cell Encapsulation and Maintenance, Bioengineering, 11(4): 375 (2024) https://doi.org/10.3390/bioengineering11040375,
  8. Oduah, S.T. Sharfstein, N. Seetharamu, S. Grossman, and L. Litovchick, Proteasome inhibition paradoxically degrades gain-of-function mutant p53 R273H in NSCLC and could have therapeutic implications, Frontiers in Oncology, 14: 1363543 (2024) doi.org/10.3389/fonc.2024.1363543 .
  9. *S.C. Rose, M. Larsen, Y. Xie, and  S.T. Sharfstein, Salivary Gland Bioengineering, Bioengineering 11: 28 (2024) https://doi.org/10.3390/bioengineering11010028
  10. Ramesh, P., Pena, R., Morrissey, J.M. et al. Cryoelectrospun elastin-alginate scaffolds as potential cell delivery vehicles for mesenchymal stromal cell therapy. Sci Rep 15, 19847 (2025). https://doi.org/10.1038/s41598-025-03822-x 

Book Chapters

  1. Hussain Dahodwala and Susan T. Sharfstein, “The ‘Omics revolution in CHO biology: Roadmap to improved CHO productivity” - revised, in Heterologous Protein Production in CHO Cells, Methods and Protocols, 2nd edition, Meleady, ed. Methods in Molecular Biology, Humana Press (2025). v2853, Ch. 9, p119-138.
  2. Ranya Pranomphon, Vijay Tejwani, Hussain Dahodwala, Montarop Yamabhai, and Susan T. Sharfstein, “Metabolic and process engineering to control glycan structures for biopharmaceuticals produced in cultured mammalian cells” in Bioprocessing, Bioengineering and Process Chemistry in the Biopharmaceutical Industry: Using Chemistry and Bioengineering to Improve the Performance of Biologics. Gadamasetti and S. A. Kolodziej, eds., Springer Nature, (2024), Ch. 6, p 135-168 https://doi.org/10.1007/978-3-031-62007-2_6

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